The rocker is parting with 29 instruments, including two pre-World War Two Martin acoustic guitars and an Epiphone Les Paul autographed by Paul himself.
Bosses at Nashville, Tennessee’s Gruhn Guitars will handle the sale of the guitars – some of which were bought from their store.
Gruhn Guitars CEO George Gruhn tells Guitar World: “Eric Clapton first visited my shop in 1970 when Derek & the Dominos performed on The Johnny Cash Show.
“He assembled his famous ‘Blackie’ Stratocaster using components from the four Stratocasters he bought from me and parts he purchased from Sho-Bud Guitars around the corner from my shop the same day.
“Over the years, Eric and I have remained in touch, made a good number of instrument deals, and he has frequently visited Gruhn Guitars when he passes through Nashville. It is very meaningful to have a friend like Eric Clapton who shares my love of guitars and uses the instrument to such great effect.
“Everyone at Gruhn Guitars feels incredibly honoured to represent him in offering a group of very fine instruments from his collection.”
It is not clear why Clapton is selling off the guitars or if a charity will benefit from the proceeds of the sales.